Hribernik, N. et al. Supramolecular Carbohydrate Assemblies with Tunable Glycan Surfaces. Angewandte Chemie 138, e15926 (2026).
Stevens, C. A. et al. Polymer Blend Controls Nanoparticles’ Surface Charge for Improved Mucus Penetration and Epithelial Cell Adhesion. Nano Letters 25, 16963–16969 (2025).
Alty, J. W. et al. Synthetic Mucins as Glycan-Defined Prebiotics. ACS Central Science 11, 918–926 (2025).
Degen, G. D. et al. Mussel-inspired cross-linking mechanisms enhance gelation and adhesion of multifunctional mucin-derived hydrogels. Science Advances 122, e2415927122 (2025).
Gonzalez La Corte, S. et al. Morphogenesis of bacterial cables in polymeric environments. PNAS 11, eadq7797 (2025).
Wheeler, K. M. et al. Mucus-derived glycans are inhibitory signals for Salmonella Typhimurium SPI-1-mediated invasion. Cell Reports 44, 116304 (2025).
Kim, M. S. et al. Modeling spatiotemporal expansion of Pseudomonas aeruginosa communities within mucin gel mimetic environments. Authorea https://doi.org/10.22541/au.174478563.33549237/v1 (2025) doi:10.22541/au.174478563.33549237/v1.
Werlang, C. A. et al. Selective Biofilm Inhibition through Mucin-Inspired Engineering of Silk Glycopolymers. Journal of American Chemical Society 146, 34661–34668 (2024).
Bath, J. et al. Mucins protect against Streptococcus pneumoniae virulence by suppressing pneumolysin expression. Journal of Clinical Investigation 134, e182769 (2024).
Pelayo, P. et al. Prevotella are major contributors of sialidases in the human vaginal microbiome. PNAS 121, (2024).
Bej, R. et al. Mucus‐Inspired Self‐Healing Hydrogels: A Protective Barrier for Cells against Viral Infection. Advanced Materials 36, 2401745 (2024).
Wu, C. M. et al. Mucin glycans drive oral microbial community composition and function. Nature Partner Journals 9, 11 (2023).
Wagner, C. E. et al. Comparison of Physicochemical Properties of Native Mucus and Reconstituted Mucin Gels. Biomacromolecules 24, 628–639 (2023).
Wang B. X. et al. Host-derived O-glycans inhibit toxigenic conversion by a virulence-encoding phage in Vibrio cholerae. The EMBO Journal 42, EMBJ2022111562 (2023).
Kramer, J. & Ribbeck K. Theme issue: In vitro mucus models. Advanced drug delivery reviews 201, 115053 (2023).
Bustos, N. A., Ribbeck, K. & Wagner, C. E. The role of mucosal barriers in disease progression and transmission. Advanced Drug Delivery Reviews 200, 115008 (2023).
Burcham L. et al. Role of MUC5B during Group B Streptococcal Vaginal Colonization. Mbio 13, e00039-22 (2022).
Takagi J. et al. Mucin O-glycans are natural inhibitors of Candida albicans pathogenicity. Nature Chemical Biology 18, 762–773 (2022).
Samad T., Witten J., Grodzinsky AJ., & Ribbeck K. Spatial configuration of charge and hydrophobicity tune particle transport through mucus. Biophysical Journal 121, 277–287 (2022).
Wang B., Cady K., Cárcamo-Oyarce G., Ribbeck K., & Laub M. Two-component signaling systems regulate diverse virulence-associated traits in Pseudomonas aeruginosa. Applied and Environmental Microbiology 87, e03089-20 (2021).
Kruger A. et al. Stereochemical Control Yields Mucin Mimetic Polymers. American Chemical Society Central Science 7, 624–630 (2021).
Werlang C. et al. Mucin glycans suppress quorum sensing pathways and genetic transformation in Streptococcus mutans. Nature Microbiology 6, 574–583 (2021).
McShane A. et al. Mucus. Current Biology 31, R938–R945 (2021).
Mawla G. et al. ClpP1P2 peptidase activity promotes biofilm formation in P. aeruginosa. Molecular Microbiology 115, 1094–1109 (2021).
Hahn G. et al. Genome-wide association analysis of COVID-19 mortality risk in SARS-CoV-2 genomes identifies mutation in the SARS-CoV-2 spike protein that colocalizes with P.1 of the Brazilian strain. Genetic Epidemiology 45, 685–693 (2021).
Wang B., Wu C., & Ribbeck K. Home, sweet home: how mucus accommodates our microbiota. FEBS 288, 1789–1799 (2020).
Wang B. et al. Mucin glycans signal through the sensor kinase RetS to inhibit virulence-associated traits in Pseudomonas aeruginosa. Current Biology 31, 1–13 (2020).
Wheeler K. et al. Mucin glycans attenuate the virulence of Pseudomonas aeruginosa in infection. Nature Microbiology 4, 2146–2154 (2019).
Witten J., Samad T., & Ribbeck K. Molecular characterization of mucus binding. ACS Biomacromolecules 4, 1505–1513 (2019).
Werlang C., Cárcamo-Oyarce G., & Ribbeck K. Engineering mucus to study and influence the microbiome. Nature Review Materials 4, 134–145 (2019).
Samad T., Co, J., Witten J., & Ribbeck K. Mucus and mucin environments reduce the efficacy of polymyxin and fluoroquinolone antibiotics. ACS Biomaterials Science & Engineering 5, 1189–1194 (2019).
Co J. et al. Mucins trigger dispersal of Pseudomonas aeruginosa biofilms. Nature Partner Journals Biofilms and Microbiomes 4, 23 (2018).
Wagner C.E., Wheeler K.M, & Ribbeck K. Mucins and their role in shaping the functions of mucus barriers. Annual Review of Cell and Developmental Biology 34, 189–215 (2018).
Witten J., Samad T., & Ribbeck K. Selective permeability of mucus barriers. Current Opinion in Biotechnology 52, 124–133 (2018).
Goodrich C., Brenner M., & Ribbeck K. Enhanced diffusion by binding to the crosslinks of a polymer gel. Nature Communications 9, (2018).
Wagner C.E., Turner B.S, Rubinstein M., McKinley G. H., & Ribbeck K. A rheological study of the of the association and dynamics of MUC5AC gels. Biomacromolecules 18, 3654–3664 (2017).
Smith-Dupont K. et al. Probing the potential of mucus permeability to signify preterm birth risk. Scientific Reports 7, 10302 (2017).
Samad T. et al. Swimming bacteria promote dispersal of non-motile staphylococcal species. The ISME Journal 11, 1933–1937 (2017).
Frenkel E.S. & Ribbeck K. Salivary mucins promote the coexistence of competing oral bacterial species. The ISME Journal 11, 1286–1290 (2017).
Zhang L., Turner B., Ribbeck K, & Ten Hagen KG. Loss of the mucosal barrier alters the progenitor cell niche via Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling. Journal of Biological Chemistry 292, 21231–21242 (2017).
Witten J. & Ribbeck K. The particle in the spider’s web: transport through biological hydrogels. Nanoscale 9, 8080–8095 (2017).
Chen W.G, Witten J., Grindy S.C., Holten-Andersen N., & Ribbeck K. Charge influences substrate recognition and self-assembly of hydrophobic FG sequences. Biophysical Journal 113, 2088–2099 (2017).
Tang S. et al. Antiviral Agents from Multivalent Presentation of Sialyl Oligosaccharides on Brush Polymers. ACS Macro Letters 5, 413–418 (2016).
Billings N., Birjiniuk A, Samad T., Doyle P., & Ribbeck K. Material properties of biofilms: a review of methods for understanding permeability and mechanics. Reports on Progress in Physics: 78(3), 036601 78, 036601 (2015).
Ahn J., Crouzier T., Ribbeck K., Rubner M.F., & Cohen R.E. Tuning the properties of mucin via layer-by-layer assembly. Biomacromolecules 16, 228–235 (2015).
Kim M. et al. Artificially Engineered Protein Hydrogels Adapted from the Nucleoporin Nsp1 for Selective Biomolecular Transport. Advanced Materials 27, 4207–4212 (2015).
Frenkel E.S. & Ribbeck K. Salivary mucins in host defense and disease prevention. Journal of Oral Microbiology 7, 29759 (2015).
Crouzier T. et al. Modulating mucin hydration and lubrication by deglycosylation and polyethylene glycol binding. Advanced Materials Interfaces 2, 1500308 (2015).
Co J., Crouzier T., & Ribbeck K. Probing the Role of Mucin-Bound Glycans in Bacterial Repulsion by Mucin Coatings. Advanced Materials Interfaces 2, 1500179 (2015).
Kavanaugh, N. L., Zhang, A. Q., Nobile, C. J., Johnson, A. D. & Ribbeck, K. Mucins Supress Virulence Traits of Candida albicans. mBio 5, e01911-14 (2014).
Jetov I., Samuelesson T., Yao G., Amsterdam A., & Ribbeck K. Zebrafish as a Model to Study Live Mucus Physiology. Scientific Reports 4, 6653 (2014).
Birjiniuk, A. et al. Single Particle Tracking Reveals Spatial and Dynamic Organization of the E. coli Biofilm Matrix. New Journal of Physics 16, 085014 (2014).
Polak R et al. Sugar-Mediated Disassembly of Mucin/Lectin Multilayers and Their Use as pH-Tolerant, On-Demand Sacrificial Layers. Biomacromolecules 15, 3093–8 (2014).
Frenkel E.S. & Ribbeck K. Salivary mucins protect surfaces from colonization by cariogenic bacteria. Applied and Environmental Microbiology: 81(1), 332-338 81, 332–338 (2014).
Crouzier T., Jang H., Ahn J., Stocker R., & Ribbeck K. Cell patterning with mucin biopolymers. Biomacromolecules 14, 3010–3016 (2013).
Li L. et al. Spatial configuration and composition of charge modulates transport into a mucin hydrogel barrier. Biophysical Journal 105, 1357–1365 (2013).
Critchfield A.S. et al. Cervical Mucus Properties Stratify Risk for Preterm Birth. PLOS ONE 8, e69528 (2013).
Billings N. et al. The extracellular matrix component Psl provides fast-acting antibiotic defense in Pseudomonas aeruginosa biofilms. PLOS Pathogens 9, e1003526 (2013).
Crouzier T, Beckwitt CH, & Ribbeck K. Mucin multilayers assembled through sugar-lectin interactions. Biomacromolecules 13, 3401–8 (2012).
Lieleg, O., Lieleg, C., Bloom, J., Buck, C. B. & Ribbeck, K. Mucin biopolymers as broad-spectrum antiviral agents. Biomacromolecules 13, 1724–1732 (2012).
Vladescu, I., Lieleg, O., Jang, S. & and Ribbeck, K. An absorption chromatography assay to probe bulk particle transport through hydrogels. Journal of Pharmaceutical Sciences 101, 436–42 (2012).
Li, L. D., Lieleg, O., Jang, S. K., Ribbeck, K. & Han, J. Microfluidic in vitro system for the quantitative study of the stomach mucus barrier. Lab Chip 12, 4071–9 (2012).
Kavanaugh, N. K. & Ribbeck, K. Selected antimicrobial essential oils eradicate Psuedomonas spp. and Staphylococcus aureus biofilms. Applied and Environmental Microbiology 78, 4057–4061 (2012).
Caldara M. et al. Mucin biopolymers prevent bacterial aggregation by retaining cells in the free-swimming state. Current Biology 22, 2325–2330 (2012).
Lieleg O. & Ribbeck K. Biological hydrogels as selective diffusion barriers. Trends in Cell Biology 21, 543–551 (2011).
Lieleg O., Caldara M., Baumgaertal R., & Ribbeck K. Mechanical robustness of Pseudomonas aeruginosa biofilms. Soft Matter 7, 3307 (2011).
Lieleg O., Vladescu I. & and Ribbeck, K. Characterization of particle translocation through mucin hydrogels. Biophysical Journal 98, 1782–1789 (2010).
Colwell L., Brenner M., & Ribbeck K. Charge as a selection criterion for translocation through nuclear pore complexes. PLoS Computational Biology 6, e1000747 (2010).
Ribbeck, K. Do viruses use vectors to penetrate mucus barriers? Bioscience Hypothesis 2, 359–362 (2009).
Pérez-Andino J., Buck C.B., & Ribbeck K. Adsorption of Human Papillomavirus 16 to live human sperm. PLoS ONE 4, e5847 (2009).
Ribbeck, K. & Mitchison, T. J. Meiotic Spindle- Sculpted by Severing. Current Biology 16, R923-5 (2007).
Ribbeck K, Raemaekers T, Carmeliet G, & Mattaj I. NuSAP can link mitotic chromatin to microtubules. Current Biology 17, 230–6 (2007).
Clausen, T. & Ribbeck, K. Self-organization of anastral spindles by synergy of dynamic instability, autocatalytic microtubule production, and a spatial signaling gradient. PLoS ONE 2, e244 (2007).
Ribbeck K et al. NuSAP, a mitotic RanGTP target that can stabilise and cross-link microtubules. Mol Biol Cell 17, 2646–2660 (2006).
Arnaoutov A et al. Crm1 is a mitotic effector of Ran-GTP in somatic cells. Nat Cell Biol 7, 626–32 (2005).
Raemaekers T et al. NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization. J Cell Biol 162, 1017–29 (2003).
Görlich D & Seewald M and Ribbeck K. Characterization of Ran-driven cargo transport and the RanGTPase system by kinetic measurement and computer simulation. EMBO J 22, 1088–110 (2003).
Ribbeck, K. & Görlich, D. The permeability barrier of nuclear pore complexes appears to operate via hydrophobic exclusion. EMBO J 21, 2664–71 (2002).
Ribbeck K and Görlich D. Kinetic analysis of translocation through nuclear pore complexes. EMBO J 20, 1320–1330 (2001).
Bachi A et al. The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates. RNA 6, 136–58 (2000).
Ribbeck K, Kutay U., & Paraskeva E. and Görlich D. The translocation of transportin-cargo complexes through nuclear pores is independent of both Ran and energy. Current Biology 9, 47–50 (1999).
Bayliss R et al. Interaction between NTF2 and xFxFG-containing nucleoporins is required to mediate nuclear import of RanGDP. J Mol Biol 293, 579–93 (1999).
Ribbeck K, Lipowsky G., Kent H. M., & Stewart M. & Görlich D. NTF2 mediates nuclear import of Ran. EMBO J 17, 6587–6598 (1998).
Ferrari MB, Ribbeck K, Hagler DJ, & Spitzer NC. A calcium signaling cascade essential for myosin thick filament assembly in Xenopus myocytes. J Cell Biol 141, 1349–56 (1998).